The play features Catharine Holly, a young woman who seems to go insane after her cousin Sebastian dies on a trip to Europe under mysterious circumstances. Sebastian's mother, Violet Venable, tries to cloud the truth about her son's homosexuality and his death, as she wants him to be remembered as a great artist. She threatens to lobotomize Catharine for her incoherent utterances relating to Sebastian's demise. Finally, under the influence of a truth serum, Catharine tells the gruesome story of Sebastian's death by cannibalism at the hand of local boys whose sexual favors he sought, an act that recalls the Dionysian sparagmos and omophagia. Both his mother and later Catharine were only devices for him to attract the young men.